HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 4-[2-[2-Methyl-4-oxo-3,4-dihydro-3-quinazolinyl]ethoxy]benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-(2-Bromoethoxy)Benzaldehyde | HCID 262706 | — |
| Reactant | 2-Methyl-4(3H)-quinazolinone | HCID 135400457 | — |
| Product | 4-[2-[2-Methyl-4-oxo-3,4-dihydro-3-quinazolinyl]ethoxy]benzaldehyde | HCID 21960134 | 39% |
Reaction Steps
The title compound (0.6 g, 39%) was prepared from 2-methyl-4-oxo-3,4-dihydroquinazoline (0.8 g, 5 mmol) and 4-[2-bromoethoxy]benzaldehyde (1.37 g, 6 mmol) in the presence of K2CO3 (1.3 g, 10.0 mmol) as base, by a similar procedure to that described in preparation 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06372750B2 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-173ae367b5c54ac0a04df6a72804633e |
| Source note | uspto-grants-2002_04 |