HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Cyclopentyloxy-4-methoxybenzaldehyde → 3-Cyclopentyloxy-4-methoxybenzyl alcohol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Cyclopentyloxy-4-methoxybenzaldehyde | HCID 2735893 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-Cyclopentyloxy-4-methoxybenzyl alcohol | HCID 11138706 | 98% |
Reaction Steps
A solution of 3-cyclopentyloxy-4-methoxybenzaldehyde (38 g 0.17 mol) in 40 ml of ethanol and sodium borohydride (1.63 g, 0.043 mol) was stirred for 2 hours at room temperature at which time the reaction was complete by TLC. The reaction was diluted with water and extracted with ethyl acetate. Evaporation of the ethyl acetate afforded 3-cyclopentyloxy-4-methoxybenzyl alcohol (37 g, 98%) suitable for the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06372770B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-76d21c5a3ee841218c48652362c01637 |
| Source note | uspto-grants-2002_04 |