Water → HCID 10157910, compound

Participants

Reaction Steps

Sodium borohydride 0.05 g, 0.0013 mol) was added to a stirred solution of 2-(3-cyclopentyloxy-4-methoxybenzyl)-5-chlorobenzoxazole-7-ethanal (1.0 g, 0.0025 mol) in 10 ml ethanol. Stirring was continued for 1 hour. Water (15 ml) was added and the reaction mixture was extracted with 2×50 ml ethyl acetate. The ethyl acetate layer was washed once with water (50 ml), dried and evaporated to give 1.1 g of pale yellow crystals. A small sample of this solid was recrystallized from a blend of ether-hexane to give the title compound as a white solid, mp 74-76° C.

Provenance & Evidence