HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminophenol → N-[4-hydroxy-3,5-di-t-butyl-phenylacetyl]-2-hydroxyaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminophenol | HCID 5801 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 3,5-Bis(1,1-dimethylethyl)-4-hydroxybenzeneacetic acid | HCID 2775110 | — |
| Product | N-[4-hydroxy-3,5-di-t-butyl-phenylacetyl]-2-hydroxyaniline | HCID 22618275 | 86.2% |
Reaction Steps
Using previously described procedures with 4-hydroxy-3,5-di-t-butyl-phenylacetic acid (45 g, 0.17 mol), 2-hydroxyaniline (20.7 g, 0.19 mol) and 1,1′-carbonyl diimidazole (29 g, 0.18 mol) the title compound (52.1 g, 86%) was obtained as a tan solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06372770B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-10e98025bd784214b312c85de6e6e20b |
| Source note | uspto-grants-2002_04 |