HCID 54250094, compound → HCID 53753805, compound

HRID 842271Notes

Reaction equation

HRID 842271 reaction equation
[C:1]([O:4][CH2:5][C:6]([NH:26][C:27](=[O:29])[CH3:28])([CH2:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[O:18]CC1C=CC=CC=1)[CH2:7][CH2:8][CH3:9])(=[O:3])[CH3:2]>C(O)C.[C].[Pd]>[C:1]([O:4][CH2:5][C:6]([NH:26][C:27](=[O:29])[CH3:28])([CH2:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[OH:18])[CH2:7][CH2:8][CH3:9])(=[O:3])[CH3:2]

Participants

4

Reactant 1

HCID 54250094HCID 54250094, compound

Product 1

HCID 53753805HCID 53753805, compoundYield 93.4%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolvent

Procedure

To a solution of 2-acetamido-2-(2-(2-benzyloxyphenyl)ethyl)pentyl acetate (0.90 g) in ethanol (45 ml), 10% palladium-carbon (0.40 g) was added and the mixture was subjected to catalytic reduction at room temperature for 6 hours. Catalyst was filtered off from the reaction solution and the solvent was distilled away under reduced pressure to give the subject compound (0.65 g).

Workup

  1. filtrationCatalyst was filtered off from the reaction solution
  2. distillationthe solvent was distilled away under reduced pressure

Sources & evidence

ORD record
ord-b08469e16ab744e8998d6d5dc27f9b04
Source dataset
uspto-grants-2002_04
Patent number
US06372800B1

Reaction notes

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