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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 842283Generated: October 30, 2026

Diethyl ethylmalonate → 2-Amino-2-ethyl-4-(4-octylphenyl)butanol

https://huagongshe.com/reaction/842283

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl ethylmalonateHCID 8610—
ReactantHCID 53718772HCID 53718772—
Product2-Amino-2-ethyl-4-(4-octylphenyl)butanolHCID 22618741—

Reaction Steps

In working example 77, 2-acetamido-2-ethyl-4-(4-octanoylphenyl)butyl acetate obtained by using ethylmalonic acid diethyl ester instead of propylmalonic acid diethyl ester, is subjected to reduction in the same manner as working example 2 (7) and then hydrolysis in the same manner as working example 78 to give the subject compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06372800B1
Source datasetuspto-grants-2002_04
ORD IDord-fc536b2b13004f55a41cb0148f2b6f51
Source noteuspto-grants-2002_04