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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 842284Generated: October 30, 2026

Diethyl ethylmalonate → 2-Amino-2-ethyl-4-[4-(1-hydroxyoctyl)phenyl]butanol

https://huagongshe.com/reaction/842284

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl ethylmalonateHCID 8610—
ReactantHCID 53718772HCID 53718772—
Product2-Amino-2-ethyl-4-[4-(1-hydroxyoctyl)phenyl]butanolHCID 22618796—

Reaction Steps

In working example 77, 2-acetamido-2-ethyl-4-(4-octanoylphenyl)butyl acetate obtained by using ethylmalonic acid diethyl ester instead of propylmalonic acid diethyl ester, is treated in the same manners as working example 79 and then working example 80 to give the subject compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06372800B1
Source datasetuspto-grants-2002_04
ORD IDord-9daf5e9ccc0046e48fb74e6352479203
Source noteuspto-grants-2002_04