反应详情

49.6 g of 2-bromo-5-methylbenzenesulfinic acid are dissolved in 400 ml of methanol and treated with an equimolar amount of NaOH in 50 ml of water. The mixture is stirred at RT for 3 hours, the solution is filtered off and subsequently the solvents are removed in vacuo. Finally, water residues are removed azeotropically with 50 ml of toluene. The solid residue is dried over P4O10 in vacuo and 54.0 g of product are obtained, mp 288-290° C. (with decomposition).

1. filtrationthe solution is filtered off
2. customsubsequently the solvents are removed in vacuo
3. customFinally, water residues are removed azeotropically with 50 ml of toluene
4. dry with materialThe solid residue is dried over P4O10 in vacuo and 54.0 g of product
5. customare obtained