Water → 3-(Pentyloxy)propane-1,2-diol
Reaction equation
[CH2:1]([O:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])[CH:2]1[O:4][CH2:3]1.[OH2:11]>[OH-].[Na+].C(O)(=O)CCCCCCCCCCC>[CH2:1]([O:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])[CH:2]([CH2:3][OH:11])[OH:4]Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Conditions
- Temperature
- 90 °C
Procedure
In a four-necked 300-ml flask, 100 g (0.69 mole) of amyl glycidyl ether obtained in Example 1, 25 g (1.39 mole) of water, 2.31 g (0.028 mole) of 48% sodium hydroxide and 5.54 g (0.028 mole) of lauric acid were charged, followed by heating to 90° C. while stirring under a nitrogen gas atmosphere. The stirring was continued for 8 hours. After excess water was distilled off, the residue was distilled under reduced pressure (100° C., 0.133 kPa), whereby 110 g (0.59 mole) of amyl glyceryl ether was obtained (yield: 86%, purity: 99%).
Workup
- distillationAfter excess water was distilled off
- distillationthe residue was distilled under reduced pressure (100° C., 0.133 kPa)
Sources & evidence
- ORD record
- ord-35df0070dbda4ff585ab023dd1819b2a
- Source dataset
- uspto-grants-2002_04
- Patent number
- US06372923B1
Reaction notes
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