Acetophenone → 1-Phenylethanol

Participants

Reaction Steps

Acetophenone (2 ml, 17 mmol) was dissolved in 2-propanol (80 ml) and purged with nitrogen. Then the catalyst solution was added followed by potassium hydroxide solution (3.3 ml of 0.1M solution in 2-propanol). The mixture was stirred at ambient temperature under nitrogen for 10 h. This gave 1-phenylethanol Yield 68%, ee 49%. The initial turnover number, integrated over 1 h, was 318 h−1.

Provenance & Evidence