HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(Tert-butyldimethylsilyloxy)-2-phthalimido-1-nitrobenzene → 5-(Tert-butyldimethylsilyloxy)-2-phthalimidoaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(Tert-butyldimethylsilyloxy)-2-phthalimido-1-nitrobenzene | HCID 18174472 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 5-(Tert-butyldimethylsilyloxy)-2-phthalimidoaniline | HCID 18174494 | 89% |
Reaction Steps
A suspension of 5-(tert-butyldimethylsilyloxy)-2-phthalimido-1-nitrobenzene (5.00 g, 12.5 mmol) and 10% palladium-on-carbon (2.5 g) in ethyl acetate (60 mL) was stirred under 1 atm of hydrogen for 16 h. The mixture was filtered through a pad of diatomaceous earth and concentrated in vacuo to yield 4.1 g (89%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06372759B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-91270a18992c4b239e57907c146c59c6 |
| Source note | uspto-grants-2002_04 |