4-t-butyldimethylsilyloxy-N2-(4-t-butylbenzoyl)-1,2-benzenediamine → 4-t-Butyldimethylsilyloxy-N2-(4-t-butylbenzoyl)-N1-(3-chloroindol-6-ylcarbonyl)-1,2-benzenediamine

Participants

Role	Name	HCID	Charge
Reactant	4-t-butyldimethylsilyloxy-N2-(4-t-butylbenzoyl)-1,2-benzenediamine	HCID 11795190	—
Reactant	3-Chloro-1H-indole-6-carboxylic acid	HCID 15543042	—
Product	4-t-Butyldimethylsilyloxy-N2-(4-t-butylbenzoyl)-N1-(3-chloroindol-6-ylcarbonyl)-1,2-benzenediamine	HCID 53858890	72.2%

Reaction Steps

Using the procedure described in Example 9, Part C, 4-t-butyldimethylsilyloxy-N2-(4-t-butylbenzoyl)-1,2-benzenediamine (750 mg, 1.9 mmol) and 3-chloroindole-6-carboxylic acid (372 mg, 1.9 mmol) yielded 790 mg (72%) of the title compound.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06372759B1
Source dataset	uspto-grants-2002_04
ORD ID	ord-d919a97e65054b1b994123c181453961
Source note	uspto-grants-2002_04