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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 842403Generated: October 30, 2026

Toluene → HCID 18373213, compound

https://huagongshe.com/reaction/842403

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantIsatoic AnhydrideHCID 8359—
Reactant6-AminoindoleHCID 256096—
SolventDimethylformamideHCID 6228—
ProductHCID 18373213HCID 1837321353%

Reaction Steps

A mixture of isatoic anhydride (5.06 g, 31 mmol), 6-aminoindole (4.103 g, 31 mmol), toluene (300 mL) and DMF (30 mL) was heated to reflux for 18 hours. The reaction was cooled, filtered, and chromatographed to yield 4.103 g (53%) of the title compound as a tan solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06372759B1
Source datasetuspto-grants-2002_04
ORD IDord-94c70336708844b085e8138569aa44dc
Source noteuspto-grants-2002_04