Hydrogen Peroxide → Benzophenone

Participants

Reaction Steps

A mixture of 5 mmol of benzhydrol, 0.5 mmol of N-hydroxyphthalimide, and 5 ml of ethyl acetate was stirred at 75° C. in an oxygen atmosphere (1 atm) for 12 hours. An iodometric analysis of a reaction mixture revealed that hydrogen peroxide was formed in yield of 50% (selectivity: 70%). Separately, as a result of a gas chromatographic analysis of the reaction mixture, the conversion rate from benzhydrol was 72%, and benzophenone was formed in yield of 71%.

Provenance & Evidence