HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene → HCID 11286510, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene | HCID 241 | — |
| Reactant | Tributylstannane | HCID 5948 | — |
| Reactant | Azobisisobutyronitrile | HCID 6547 | — |
| Reactant | HCID 11323077 | HCID 11323077 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 11286510 | HCID 11286510 | — |
Reaction Steps
reacting said (1R,2R,4S,5S)-4-iodo-2-methyl-6-oxabicyclo[3.2.1]octan-7-one (8) with n-Bu3SnH and catalytic AIBN in refluxing benzene, or with Raney Nickel in the presence of pyridine under 50 psi H2, to produce (1R,2R,5R)-2-methyl-6-oxabicyclo[3.2.1]octan-7-one (9),
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06375943B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-ec9ea23b0ef04726acf41f3e935a7100 |
| Source note | uspto-grants-2002_04 |