Hydrogen Bromide → HCID 70160773, compound

Participants

Reaction Steps

The product from Example 1D (19 g, 42.4 mmol) in 1,4-dioxane (100 mL) at 10° C. was treated with 30% HBr in acetic acid (30 mL), stirred for 30 minutes, purged with nitrogen, poured into diethyl ether (600 mL), triturated, and filtered to provide the title compound. 1H NMR (300 MHz, DMSO-d6) δ1.60 (d, 3H), 3.98 (d, 1H), 4.20 (d, 1H), 4.38 (q, 1H), 5.14 (s, 2H), 7.16 (t, 1H), 7.25 (d, 1H), 7.40-7.55 (m, 5H), 7.63 (t, 1H), 7.91 (d,1H), 9.20-9.60 (bs, 2H).

Provenance & Evidence