Methylhydrazine → 1-Methyl-1H-indazole-6-carbonitrile

HRID 842716Notes

Reaction equation

HRID 842716 reaction equation
[C:1]([C:3]1[CH:10]=[CH:9][C:6]([CH:7]=O)=[C:5](F)[CH:4]=1)#[N:2].[CH3:12][NH:13][NH2:14]>>[C:1]([C:3]1[CH:4]=[C:5]2[C:6]([CH:7]=[N:14][N:13]2[CH3:12])=[CH:9][CH:10]=1)#[N:2]

Participants

3

Reactant 2

HCID 6061MethylhydrazineHCID 27831503-Fluoro-4-formylbenzonitrile

Product 1

HCID 226152671-Methyl-1H-indazole-6-carbonitrile

Procedure

The title compound was prepared according to the method described in Example 8, Step A, 4-cyano-2-fluorobenzaldehyde and methyl hydrazine as starting materials: 1H NMR (CDCl3) δ 8.07 (s, 1H), 7.83 (d, J=8.2 Hz, 1H), 7.79 (s, 1H), 7.37 (d, J=8.3 Hz, 1H), 4.14 (s, 3H).

Sources & evidence

ORD record
ord-83ed7fff0a7c445f9094f2cdfc59572b
Source dataset
uspto-grants-2002_04
Patent number
US06376499B1

Reaction notes

Loading…