5-(3-Tert-butoxycarbonylaminopropyl)-tetrahydrofuran-2-carboxylic acid methyl ester → 5-(3-Amino-propyl)-tetrahydrofuran-2-carboxylic acid methyl ester hydrochloride salt

HRID 842741Notes

Reaction equation

HRID 842741 reaction equation
[CH3:1][O:2][C:3]([CH:5]1[CH2:9][CH2:8][CH:7]([CH2:10][CH2:11][CH2:12][NH:13]C(OC(C)(C)C)=O)[O:6]1)=[O:4].[ClH:21].COC(C1OC(CCCN)=CC=1)=O>>[ClH:21].[CH3:1][O:2][C:3]([CH:5]1[CH2:9][CH2:8][CH:7]([CH2:10][CH2:11][CH2:12][NH2:13])[O:6]1)=[O:4]

Participants

3

Reactant 2

HCID 542351595-(3-Tert-butoxycarbonylaminopropyl)-tetrahydrofuran-2-carboxylic acid methyl esterHCID 692922505-(3-Amino-propyl)-furan-2-carboxylic acid methyl ester hydrochloride salt

Product 1

HCID 695448005-(3-Amino-propyl)-tetrahydrofuran-2-carboxylic acid methyl ester hydrochloride salt

Procedure

The title compound was prepared from 5-(3-tert-butoxycarbonylamino-propyl)-tetrahydrofuran-2-carboxylic acid methyl ester following the procedure described in Step C for Preparation 2a.

Sources & evidence

ORD record
ord-7a743d12dee9447481e506fb70915d32
Source dataset
uspto-grants-2002_04
Patent number
US06376502B1

Reaction notes

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