HCID 178478098, compound → HCID 178420213, compound

HRID 842756Notes

Reaction equation

HRID 842756 reaction equation
Cl[C:2]1[CH:7]=[CH:6][CH:5]=[C:4](Cl)[C:3]=1[CH2:9][C:10]1[NH:14][N:13]=[N:12][N:11]=1>[Pd].CO>[C:3]1([CH2:9][C:10]2[NH:14][N:13]=[N:12][N:11]=2)[CH:2]=[CH:7][CH:6]=[CH:5][CH:4]=1

Participants

4

Reactant 1

HCID 178478098HCID 178478098, compound

Product 1

HCID 178420213HCID 178420213, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

The mixture of 5-(2,6-dichlorophenylmethyl)tetrazole (355 mg), 5% palladium on activated carbon (93 mg) and methanol (8 ml) was stirred for 1 h room temperature under an atmosphere of hydrogen gas. The reaction mixture was filtered through Celite (trade mark) and the filtrate was concentrated to give the title compound having the following physical data.

Workup

  1. filtrationThe reaction mixture was filtered through Celite (trade mark)
  2. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-dbca2720337a4c9a98eaadeb62c55c46
Source dataset
uspto-grants-2002_04
Patent number
US06376484B1

Reaction notes

Loading…