4-Hydrazinylbenzenesulfonamide hydrochloride → HCID 9864112, compound

HRID 842798Notes

Reaction equation

HRID 842798 reaction equation
[F:1][C:2]([F:14])([F:13])[C:3](=O)/[CH:4]=[CH:5]/[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.Cl.[S:16]([C:20]1[CH:25]=[CH:24][C:23]([NH:26][NH2:27])=[CH:22][CH:21]=1)(=[O:19])(=[O:18])[NH2:17]>>[S:16]([C:20]1[CH:21]=[CH:22][C:23]([N:26]2[CH:5]([C:6]3[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=3)[CH2:4][C:3]([C:2]([F:14])([F:13])[F:1])=[N:27]2)=[CH:24][CH:25]=1)(=[O:19])(=[O:18])[NH2:17]

Participants

3

Reactant 2

HCID 27945674-Hydrazinylbenzenesulfonamide hydrochlorideHCID 60060523-Buten-2-one,1,1,1-trifluoro-4-phenyl-

Product 1

HCID 9864112HCID 9864112, compoundYield 73%

Procedure

A solution of trans-1,1,1-trifluoro-4-phenyl-3-buten-2-one (5 mmol) and 4-sulfamylphenyl hydrazine hydrochloride (6 mmol) was subjected to Procedure 3. The title compound was obtained in 73% yield, m.p. 132-135° C.; C, H analysis (C18H15SO2N4F3.H2O):

Sources & evidence

ORD record
ord-bf603d7ec442418bbb1c21c63e181ca6
Source dataset
uspto-grants-2002_04
Patent number
US06376519B1

Reaction notes

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