HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydrazinylbenzenesulfonamide hydrochloride → 4-[3-(1H-indol-3-yl)-5-(trifluoromethyl)-3,4-dihydropyrazol-2-yl]benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydrazinylbenzenesulfonamide hydrochloride | HCID 2794567 | — |
| Reactant | TRANS-1,1,1-TRIFLUORO-4-(3-INDOLYL)-3-BUTEN-2-ONE | HCID 5709225 | — |
| Product | 4-[3-(1H-indol-3-yl)-5-(trifluoromethyl)-3,4-dihydropyrazol-2-yl]benzenesulfonamide | HCID 9866143 | 82% |
Reaction Steps
A solution of trans-1,1,1-trifluoro-4-(3-indolyl)-3-buten-2-one (5 mmol) and 4-sulfamylphenyl hydrazine hydrochloride (6 mmol) was subjected to Procedure 3. The title compound was obtained in 82% yield, m.p. 178-180° C.; C, H analysis (C16H14SO2N4F3):
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06376519B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-f901ffc4891847c197e038f7399fd8bd |
| Source note | uspto-grants-2002_04 |