HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 842800Generated: October 30, 2026
3-Hydroxybenzyl alcohol → Benzenemethanol, 3-(2-quinolinylmethoxy)-
https://huagongshe.com/reaction/842800
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Hydroxybenzyl alcohol | HCID 102 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-(Chloromethyl)quinoline hydrochloride | HCID 3083823 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Benzenemethanol, 3-(2-quinolinylmethoxy)- | HCID 14650410 | — |
Reaction Steps
A mixture of 12.8 g (0.06 mol) of 2-quinolinylmethyl chloride HCl, 7.5 g (0.06 mol) of 3-hydroxybenzyl alcohol, and 18 g of potassium carbonate in 50 ml of DMF is heated at 70° C. overnight. The reaction mixture is poured into water, and the precipitated product is collected, filtered and dried to give 3-(2-quinolinylmethyloxy)benzyl alcohol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06376512B1 |
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| Source dataset | uspto-grants-2002_04 |
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| ORD ID | ord-1c84b44130cf40dca65386dd05251bb5 |
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| Source note | uspto-grants-2002_04 |
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