Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | HCID 14774158 | HCID 14774158 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | HCID 14774159 | HCID 14774159 | — |
Reaction Steps
A mixture of 1 g of ethyl [5-(4-(3-(2-quinolinylmethyl-oxy)phenoxymethyl)phenyl)tetrazol-3-yl]acetate in 5 ml ethanol and 40 ml of 1N NaOH is stirred at 70° C. for 4 hours. This is cooled, diluted with water, acidified with acetic acid, filtered, washed with water, and then ethyl acetate to give 5-(4-(3-(2-quinolinylmethyloxy)phenoxymethyl)phenyl)tetrazol-3-yl acetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06376512B1 |
|---|
| Source dataset | uspto-grants-2002_04 |
|---|
| ORD ID | ord-6160b8937b364287a94af8ba912a6fc2 |
|---|
| Source note | uspto-grants-2002_04 |
|---|
