Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | Pyridinium chloride | HCID 10176127 | — |
| Reactant | HCID 14774175 | HCID 14774175 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178522023 | HCID 178522023 | — |
Reaction Steps
A mixture of 10 mmol of 3-(3-(2-quinolinylmethyloxy)benzoylamino)benzonitrile, 50 mmol of sodium azide, and 50 mmol of pyridine HCl in 30 ml of DMF is heated at 100° C. for 2 days. The reaction mixture is poured into water, and the product is collected on a filter. Recrystallization from ethyl acetate and DMF gives 5-(3-(3-(2-quinolinylmethyloxy)benzoylamino)phenyl)tetrazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06376512B1 |
|---|
| Source dataset | uspto-grants-2002_04 |
|---|
| ORD ID | ord-904924a0ac5643cf84420514ecc19c3f |
|---|
| Source note | uspto-grants-2002_04 |
|---|
