HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Methoxyphenyl)boronic acid → N-(3-methyl-5-isoxazolyl)-4-(4-methoxyphenyl)benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Methoxyphenyl)boronic acid | HCID 201262 | — |
| Reactant | N-(3-methyl-5-isoxazolyl)-4-bromobenzenesulfonamide | HCID 15453181 | — |
| Product | N-(3-methyl-5-isoxazolyl)-4-(4-methoxyphenyl)benzenesulfonamide | HCID 15453186 | 82% |
Reaction Steps
N-(3-methyl-5-isoxazolyl)-4-(4-methoxyphenyl)benzenesulfonamide was prepared in the same manner as described in Example 14b, using N-(3-methyl-5-isoxazolyl)-4-bromobenzenesulfonamide (Example 14a) and 4-methoxybenzeneboronic acid resulting in an 82% yield of the final product, m.p. 194-196° C. The product was recrystallized using hexane/ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06376523B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-562bf2f615bf49299f327ee7aefae2f5 |
| Source note | uspto-grants-2002_04 |