HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Butoxybenzenesulfonyl Chloride → 4-Butoxy-N-(4-bromo-3-methyl-5-isoxazolyl)benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Butoxybenzenesulfonyl Chloride | HCID 517990 | — |
| Reactant | 4-Bromo-3-methylisoxazol-5-amine | HCID 10487519 | — |
| Product | 4-Butoxy-N-(4-bromo-3-methyl-5-isoxazolyl)benzenesulfonamide | HCID 15453208 | 33% |
Reaction Steps
4-Butoxy-N-(4-bromo-3-methyl-5-isoxazolyl)benzenesulfonamide was prepared from 5-amino-4-bromo-3-methylisoxazole and 4-butoxybenzenesulfonyl chloride according to the procedures described in Example 30. The crude product was purified by recrystallization from ethyl acetate/hexanes to give a crystalline solid, m.p. 98-100° C., yield 33%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06376523B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-fc68b43b92464b629f75030779ed94bb |
| Source note | uspto-grants-2002_04 |