Benzenesulfonyl chloride → HCID 22616246, compound

HRID 842919Notes

Reaction equation

[NH2:1][C:2]1[C:6]([I:7])=[C:5]([CH3:8])[O:4][N:3]=1.[C:9]1([S:15](Cl)(=[O:17])=[O:16])[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[I:7][C:6]1[C:2]([NH:1][S:15]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)(=[O:17])=[O:16])=[N:3][O:4][C:5]=1[CH3:8]

Participants

Reactant 2

HCID 7369Benzenesulfonyl chloride

HCID 186173504-Iodo-5-methyl-1,2-oxazol-3-amine

Product 1

HCID 22616246HCID 22616246, compound

Procedure

N-(4-Iodo-5-methyl-3-isoxazolyl)benzenesulfonamide was prepared from 3-amino-4-iodo-5-methylisoxazole and benzenesulfonyl chloride according to the procedures described in Example 25b. The crude product was purified by recrystallization from ethyl acetate/hexanes to give a brown powder m.p. 138-141° C., yield 46%.

Workup

customThe crude product was purified by recrystallization from ethyl acetate/hexanes

Sources & evidence

ORD record: ord-04e180347fa74cfb990ac32ed9be14f2
Source dataset: uspto-grants-2002_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06376523B1

Reaction notes

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