HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Trifluoromethyl)benzenesulfonyl chloride → HCID 15453212, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Trifluoromethyl)benzenesulfonyl chloride | HCID 2733250 | — |
| Reactant | 4-Bromo-3-methylisoxazol-5-amine | HCID 10487519 | — |
| Product | HCID 15453212 | HCID 15453212 | 83% |
Reaction Steps
3-Trifluoromethyl-N-(4-bromo-3-methyl-5-isoxazolyl)benzenesulfonamide was prepared from 5-amino-4-bromo-3-methylisoxazole and 3-trifluoromethylbenzenesulfonyl chloride according to the procedures described in Example 30. The crude product was purified by recrystallization from ethyl acetate/hexanes to give a crystalline solid, m.p. 113-115° C., yield 83%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06376523B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-46a973d68a08450b99e42556120b7070 |
| Source note | uspto-grants-2002_04 |