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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 843089Generated: October 25, 2026

(4-Fluorophenyl)hydrazine → 5-Amino-1-(2,4-difluorophenyl)-4-(2-methylfuran-3-oyl)-pyrazole

https://huagongshe.com/reaction/843089

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Fluorophenyl)hydrazineHCID 69982—
Reactant(2,4-Difluoro-phenyl)-hydrazineHCID 588958—
Reactant3-(2-Methyl-3-Furyl)-3-OxopropanenitrileHCID 736755—
Product5-Amino-1-(2,4-difluorophenyl)-4-(2-methylfuran-3-oyl)-pyrazoleHCID 22262757—

Reaction Steps

Proceeding as described in Example 1, step 2, but replacing 2-(3-bromobenzoyl)acetonitrile with 2-(2-methyl-3-furanoyl)acetonitrile and substituting 4-fluorophenylhydrazine in step 3 with 2,4-difluorophenylhydrazine was obtained 5-amino-1-(2,4-difluorophenyl)-4-(2-methylfuran-3-oyl)-pyrazole (116).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06376527B1
Source datasetuspto-grants-2002_04
ORD IDord-5f3ae2c10186477c8cd734e57bc6a874
Source noteuspto-grants-2002_04