HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Fluorophenyl)hydrazine → 5-Amino-1-(2,4-difluorophenyl)4-(6-quinolinoyl)-pyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Fluorophenyl)hydrazine | HCID 69982 | — |
| Reactant | (2,4-Difluoro-phenyl)-hydrazine | HCID 588958 | — |
| Reactant | 3-Oxo-3-(quinolin-6-yl)propanenitrile | HCID 22262807 | — |
| Product | 5-Amino-1-(2,4-difluorophenyl)4-(6-quinolinoyl)-pyrazole | HCID 22262817 | — |
Reaction Steps
Proceeding as described in Example 1, step 2, but replacing 2-(3-bromobenzoyl)acetonitrile with 2-(6-quinolinoyl)acetonitrile and substituting 4-fluorophenylhydrazine in step 3 with 2,4-difluorophenylhydrazine was obtained 5-amino-1-(2,4-difluorophenyl)-4-(6-quinolinoyl)-pyrazole.HCl (117) (mpt. 220-259.2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06376527B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-51c5128c1c234108ac2cb144b38b2f1f |
| Source note | uspto-grants-2002_04 |