Hydrochloric Acid → HCID 22169207, compound

Participants

Reaction Conditions

Reaction Steps

1.95 g (0.006 mol) of ethyl 2-[4(4-cyanophenylazo)phenoxy]-ethanoate was dissolved in a mixture of 100 mL of dimethylformamide and 20 mL of water in a 250 mL one-neck round flask fitted with a magnetic stirring bar and a reflux condenser by heating to 90° C. while stirring on an oil bath. 1.3 g (0.033 mol) of NaOH was added. Stirring and heating were continued for ½ h. After cooling on an ice-water bath 6 mL of 6 N HCl was added. The precipitated crude product was recovered by filtration. The precipitate was suspended in a mixture of 10 mL of ethanol and 3 mL of water for 15 min. and filtered. The filtercake was washed with 10 mL of cold ethanol. After drying under vacuum overnight 1.17 g (yield 69%) of 2-[4-(4-cyanophenylazo)phenoxy]-ethanoic acid was obtained

Provenance & Evidence