Benzene → Nitrobenzene

HRID 843385Notes

Reaction equation

HRID 843385 reaction equation
[CH:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[N+:7]([O-])([OH:9])=[O:8]>O>[N+:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)([O-:9])=[O:8]

Participants

4

Reactant 2

HCID 241BenzeneHCID 944Nitric Acid

Product 1

HCID 7416Nitrobenzene

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Benzene (25 ml) was taken in a 50 ml two-necked round-bottomed flask equipped with a Dean-Stark apparatus. Fuming nitric acid (17 ml) was added dropwise into the reaction mixture and the reaction mixture was heated to reflux where upon the required amount of liberated water is collected in the Dean-Stark apparatus which usually takes 2 hrs. Later on, the catalyst was filtered and the reaction mixture was concentrated to obtain nitrobenzene.

Workup

  1. customequipped with a Dean-Stark apparatus
  2. temperaturethe reaction mixture was heated
  3. customis collected in the Dean-Stark apparatus which usually takes 2 hrs
  4. filtrationLater on, the catalyst was filtered
  5. concentrationthe reaction mixture was concentrated

Sources & evidence

ORD record
ord-32040236300846a39fdcfef08487089b
Source dataset
uspto-grants-2002_04
Patent number
US06376726B1

Reaction notes

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