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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 843452Generated: October 31, 2026

Methanesulfonyl chloride → 1-(Chloromethyl)-3-fluoro-2-methoxybenzene

https://huagongshe.com/reaction/843452

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanesulfonyl chlorideHCID 31297—
Reactant(3-Fluoro-2-methoxyphenyl)methanolHCID 22505951—
Product1-(Chloromethyl)-3-fluoro-2-methoxybenzeneHCID 22505963—

Reaction Steps

In an analogous manner to that described in (γ) (3-fluoro-2-methoxy-phenyl)-methanol was treated with mesylchloride to obtain 1-chloromethyl-3-fluoro-2-methoxy-benzene as a colorless liquid; MS: 174 (M)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06376672B1
Source datasetuspto-grants-2002_04
ORD IDord-ea93d8410ced4a278d55f4af08f92629
Source noteuspto-grants-2002_04