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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 843454Generated: October 25, 2026

Methyl iodide → 1-(3,5-Difluoro-2-methoxyphenyl)ethanone

https://huagongshe.com/reaction/843454

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
Reactant1-(3,5-Difluoro-2-hydroxyphenyl)ethan-1-oneHCID 2736976—
Product1-(3,5-Difluoro-2-methoxyphenyl)ethanoneHCID 18755440—

Reaction Steps

In an analogous manner to that described in (α) 1-(3,5-difluoro-2-hydroxy-phenyl)-ethanone was alkylated with methyliodide to yield 1-(3,5-difluoro-2-methoxy-phenyl)-ethanone as beige needles; MS: 186 (M)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06376672B1
Source datasetuspto-grants-2002_04
ORD IDord-e1f89bd63c74452eaaf77d56c6f7abf1
Source noteuspto-grants-2002_04