HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Peroxide → Bis[1-(2-hydroxy-2-methylpropoxy)-2,2,6,6-tetramethylpiperidin-4-yl] Succinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Peroxide | HCID 784 | — |
| Reactant | tert-Butanol | HCID 6386 | — |
| Reactant | Sodium Sulfite | HCID 24437 | — |
| Reactant | Bis(1-hydroxy-2,2,6,6-tetramethylpiperidin-4-yl) butanedioate | HCID 326921 | — |
| Product | Bis[1-(2-hydroxy-2-methylpropoxy)-2,2,6,6-tetramethylpiperidin-4-yl] Succinate | HCID 54162330 | — |
Reaction Steps
Aqueous hydrogen peroxide is added to a mixture of bis(1-oxyl-2,2,6,6-tetramethyl-pieridin-4-yl) succinate and ferrous chloride tetrahydrate in tert-butyl alcohol at 30-50° C. Excess peroxide is decomposed with aqueous sodium sulfite solution. The organic layer is concentrated and the crude product is purified by flash chromatography on silica gel to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06376584B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-1c2972790cd44edfb453f068887df733 |
| Source note | uspto-grants-2002_04 |