Methane → HCID 86757983, compound

Participants

Reaction Steps

9 cm3 of distilled water are added to an oily suspension of 2.4 g of methyl 4-(N,N-di-n-propylaminomethylene)benzoate in 9 cm3 of concentrated hydrochloric acid (36% minimum), at a temperature close to 20° C. The reaction mixture is heated under reflux for 24 hours and then supplemented with 3S charcoal, and filtered while hot on a sintered glass. The filtrate is concentrated to dryness under reduced pressure (about 1 kPa) at a temperature close to 40° C. The white solid thus obtained is filtered on sintered glass, rinsed with 3 times 10 cm3 of acetonitrile, 10 cm3 of diisopropyl ether, air-dried and then dried under reduced pressure (about 0.2 kPa) at a temperature close to 50° C. 1.8 g of 4-(N,N-di-n-propylaminomethylene)benzoic acid (monohydrochloride) are thus obtained in the form of white crystals.

Provenance & Evidence