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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 843778Generated: October 30, 2026

Propyl chloroformate → 5-(propoxycarbonyl)amino-3-(1-methylpiperidin-4-yl)-1H-indole

https://huagongshe.com/reaction/843778

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropyl chloroformateHCID 7998—
Reactant3-(1-Methylpiperidin-4-yl)-1h-indol-5-amineHCID 11831220—
Product5-(propoxycarbonyl)amino-3-(1-methylpiperidin-4-yl)-1H-indoleHCID 2261140781.3%

Reaction Steps

Beginning with 10 mg (0.0437 mMol) 5-amino-3-(1-methylpiperidin-4-yl)-1H-indole and 5.62 mg (0.0458 mMol) propyl chloroformate, 11.2 mg (81%) of the title compound were recovered.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06380201B1
Source datasetuspto-grants-2002_04
ORD IDord-e920e47b637849dfb9343f4203e8bfad
Source noteuspto-grants-2002_04