Butyl isocyanate → HCID 53692266, compound

HRID 843788Notes

Reaction equation

HRID 843788 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1.[CH2:18]([N:22]=[C:23]=[O:24])[CH2:19][CH2:20][CH3:21]>>[CH2:18]([NH:22][C:23]([NH:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1)=[O:24])[CH2:19][CH2:20][CH3:21]

Participants

3

Reactant 2

HCID 8110Butyl isocyanateHCID 118312203-(1-Methylpiperidin-4-yl)-1h-indol-5-amine

Product 1

HCID 53692266HCID 53692266, compoundYield 96%

Procedure

Beginning with 15.0 mg (0.0655 mMol) 5-amino-3-(1-methylpiperidin-4-yl)-1H-indole and 11.1 mg (0.131 mMol) n-butyl isocyanate, 20.6 mg (96%) of the title compound were recovered.

Sources & evidence

ORD record
ord-41801fb724b541f5ad1aaffd4c544a25
Source dataset
uspto-grants-2002_04
Patent number
US06380201B1

Reaction notes

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