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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 843789Generated: October 30, 2026

Cyclohexyl isocyanate → N-cyclohexyl-N'-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)urea

https://huagongshe.com/reaction/843789

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexyl isocyanateHCID 18502—
Reactant3-(1-Methylpiperidin-4-yl)-1h-indol-5-amineHCID 11831220—
ProductN-cyclohexyl-N'-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)ureaHCID 2261122287%

Reaction Steps

Beginning with 15.0 mg (0.0655 mMol) 5-amino-3-(1-methylpiperidin-4-yl)-1H-indole and 16.37 mg (0.131 mMol) cyclohexyl isocyanate, 20.1 mg (87%) of the title compound were recovered.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06380201B1
Source datasetuspto-grants-2002_04
ORD IDord-510a7ed6213e492b933fd0ee4d99f6bc
Source noteuspto-grants-2002_04