Propionic Acid → HCID 22611250, compound

HRID 843823Notes

Reaction equation

HRID 843823 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1.[C:18](O)(=[O:21])[CH2:19][CH3:20]>>[C:18]([NH:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1)(=[O:21])[CH2:19][CH3:20]

Participants

3

Reactant 2

HCID 1032Propionic AcidHCID 118312203-(1-Methylpiperidin-4-yl)-1h-indol-5-amine

Product 1

HCID 22611250HCID 22611250, compoundYield 91.1%

Procedure

Beginning with 12.0 mg (0.05 mMol) 5-amino-3-(1-methylpiperidin-4-yl)-1H-indole and 8 μL (0.1 mMol) 1-propanoic acid, 13.0 mg (91%) of the title compound were recovered.

Sources & evidence

ORD record
ord-4dbc51fa6b7a42a6883b225d770f666a
Source dataset
uspto-grants-2002_04
Patent number
US06380201B1

Reaction notes

Loading…