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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 843833Generated: October 30, 2026

Cyclohexanecarboxylic acid → 5-(cyclohexanecarbonyl)amino-3-(1-methylpiperidin-4-yl)-1H-indole

https://huagongshe.com/reaction/843833

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexanecarboxylic acidHCID 7413—
Reactant3-(1-Methylpiperidin-4-yl)-1h-indol-5-amineHCID 11831220—
Product5-(cyclohexanecarbonyl)amino-3-(1-methylpiperidin-4-yl)-1H-indoleHCID 22611522—

Reaction Steps

Beginning with 12.0 mg (0.05 mMol) 5-amino-3-(1-methylpiperidin-4-yl)-1H-indole and 13.0 mg (0.10 mMol) cyclohexanecarboxylic acid, 20.6 mg (100+%) of the title compound were recovered.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06380201B1
Source datasetuspto-grants-2002_04
ORD IDord-65ab2ab3c8dd499b9333b2a490763ea7
Source noteuspto-grants-2002_04