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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 843944Generated: October 30, 2026

6-benzyloxy-3-amino-1,2,3,4-tetrahydro-9H-carbazole → 6-benzyloxy-3-(2-(1-isopropyl-1H-pyrazol-4-yl)ethyl)amino-1,2,3,4-tetrahydro-9H-carbazole

https://huagongshe.com/reaction/843944

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-benzyloxy-3-amino-1,2,3,4-tetrahydro-9H-carbazoleHCID 22611308—
Reactant2-(1-isopropyl-1H-pyrazol-4-yl)-1-mesyloxyethaneHCID 22611512—
Product6-benzyloxy-3-(2-(1-isopropyl-1H-pyrazol-4-yl)ethyl)amino-1,2,3,4-tetrahydro-9H-carbazoleHCID 2261118563.4%

Reaction Steps

Beginning with 0.698 gm (2.39 mMol) 6-benzyloxy-3-amino-1,2,3,4-tetrahydro-9H-carbazole and 0.787 gm (3.39 mMol) 2-(1-isopropyl-1H-pyrazol-4-yl)-1-mesyloxyethane, 0.649 gm (63.4%) of the desired compound were prepared by the procedure described in detail in EXAMPLE B-72.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06380201B1
Source datasetuspto-grants-2002_04
ORD IDord-d2488780fb504370a06dcaba5e84011c
Source noteuspto-grants-2002_04