HuagongsheHuagongshe Chemistry Print Report · For research reference only
2(3H)-Benzoxazolone, 6-nitro- → 6-amino-1,3-benzoxazol-2(3H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2(3H)-Benzoxazolone, 6-nitro- | HCID 78419 | — |
| Reactant | Tin atom | HCID 5352426 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Water | HCID 962 | — |
| Product | 6-amino-1,3-benzoxazol-2(3H)-one | HCID 826989 | 35.5% |
Reaction Steps
A solution of 6-Nitro-3H-benzooxazol-2-one (8.4 grams, 46.0 mmole) and Tin (16.0 g) in concentrated hydrochloric acid (100 ml) was stirred at 60° C. for 2 hours. The mixture was diluted with water, basified to pH 12 and extracted with ethyl acetate. The combined extracts were dried over Na2SO4, filtered, and concentrated to give an orange solid (2.45 g). MW 150; MS (m/e) 151 (M++1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06380218B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-e74c0e2095b94353a822c60138a48eb3 |
| Source note | uspto-grants-2002_04 |