2-Fluoro-5-methoxybenzonitrile → 2-Fluoro-5-hydroxybenzonitrile

HRID 844007Notes

Reaction equation

HRID 844007 reaction equation
[F:1][C:2]1[CH:9]=[CH:8][C:7]([O:10]C)=[CH:6][C:3]=1[C:4]#[N:5]>CCOCC>[F:1][C:2]1[CH:9]=[CH:8][C:7]([OH:10])=[CH:6][C:3]=1[C:4]#[N:5]

Participants

3

Reactant 1

HCID 27745462-Fluoro-5-methoxybenzonitrile

Product 1

HCID 226124102-Fluoro-5-hydroxybenzonitrile

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The compound of Preparation 200 was prepared according to the procedure of Preparation 199 substituting the corresponding ether for 2-Fluoro-5-methoxy-benzonitrile. The duration of reaction was between 1 and 24 hours.

Workup

  1. customThe compound of Preparation 200
  2. customwas prepared
  3. customThe duration of reaction
  4. waitwas between 1 and 24 hours

Sources & evidence

ORD record
ord-75fae96e5d4a4711b868d67382c78718
Source dataset
uspto-grants-2002_04
Patent number
US06380218B1

Reaction notes

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