HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 844015Generated: October 30, 2026
N-bromobutanimide → HCID 22612209, compound
https://huagongshe.com/reaction/844015
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 3,5-Dichloro-2-methylthiophene | HCID 12875265 | — |
| Catalyst | Benzoyl Peroxide | HCID 7187 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | HCID 22612209 | HCID 22612209 | 55.3% |
Reaction Steps
A solution of 3,5-Dichloro-2-methyl-thiophene (1.3 grams, 7.8 mmole), NBS (1.4 grams, 7.8 mmole) and benzoyl peroxide (0.065 g) in carbon tetrachloride (40 ml) was refluxed for 18 hours. The mixture was cooled to 0° C., diluted with 40 ml hexane and filtered. The filtrate was concentrated to an oil which was purified via flash chromatography on silica using hexane as eluent to give an oil (1.06 g). MW 245.95; MS (m/e) 246 (M++1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06380218B1 |
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| Source dataset | uspto-grants-2002_04 |
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| ORD ID | ord-bbdb5362085947d6a1a13b12be82f353 |
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| Source note | uspto-grants-2002_04 |
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