HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methoxy-3-methylbenzo[d]isoxazole → 3-Methylbenzo[d]isoxazol-5-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methoxy-3-methylbenzo[d]isoxazole | HCID 18377499 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Hydrogen Bromide | HCID 260 | — |
| Product | 3-Methylbenzo[d]isoxazol-5-ol | HCID 22612034 | 138.6% |
Reaction Steps
A mixture of 5-Methoxy-3-methyl-benzo(d)isoxazole (4.9 g, 0.03 mol.) in 48% hydrobromic acid (20 mL) and acetic acid (20 mL) was refluxed for 4 hrs. The mixture was concentrated to give 6.2 g solid. MS (m/e): 149 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06380218B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-081a901239854ac7beafaf97f02f3b19 |
| Source note | uspto-grants-2002_04 |