Acetic Anhydride → HCID 136383534, compound

HRID 844026Notes

Reaction equation

HRID 844026 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH3:9])=[CH:4][C:3]=1[C:10](=[N:12][OH:13])[CH3:11].[C:14](OC(=O)C)(=[O:16])[CH3:15]>>[C:14]([O:13][N:12]=[C:10]([C:3]1[CH:4]=[C:5]([O:8][CH3:9])[CH:6]=[CH:7][C:2]=1[OH:1])[CH3:11])(=[O:16])[CH3:15]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 50827821-(2-Hydroxy-5-methoxyphenyl)ethanone oxime

Product 1

HCID 136383534HCID 136383534, compound

Conditions

Temperature
50 °C

Procedure

A mixture of 1-(2-Hydroxy-5-methoxy-phenyl)-ethanone oxime (13.7 g, 0.076 mol.) and acetic anhydride (50 mL) was heated at 50° C. for 10 min. The mixture was cooled to 0° C., filtered, and the filtrant washed with water (50 mL) and dried to give 15.5 g solid. MS (m/e): 224 (M++1), 164 (100).

Workup

  1. temperatureThe mixture was cooled to 0° C.
  2. filtrationfiltered
  3. washthe filtrant washed with water (50 mL)
  4. customdried

Sources & evidence

ORD record
ord-7487cb8f3cb64b0e961b94f95e6397da
Source dataset
uspto-grants-2002_04
Patent number
US06380218B1

Reaction notes

Loading…