HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(1,3-Benzodioxol-5-yloxy)pyridine-3-carboxylic acid → (+)-2-(Benzo[1,3]dioxol-5-yloxy)-N-[4-(1-hydroxy-ethyl)-cyclohexylmethyl]-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(1,3-Benzodioxol-5-yloxy)pyridine-3-carboxylic acid | HCID 2736879 | — |
| Reactant | HCID 178468162 | HCID 178468162 | — |
| Product | (+)-2-(Benzo[1,3]dioxol-5-yloxy)-N-[4-(1-hydroxy-ethyl)-cyclohexylmethyl]-nicotinamide | HCID 22612257 | — |
Reaction Steps
Prepared from 2-(Benzo[1,3]dioxol-5-yloxy)-nicotinic acid and (+)-trans-1-(4-Aminomethyl-cyclohexyl)-ethanol. 1HNMR (CDCl3) δ0.97 (1,m), 1.10 (3, m), 1.17 (4, m), 1.19 (4,m), 3.23 (1,t), 3.44(2,q), 6.00(2,s), 6.58 (1, dd), 6.64 (1,s), 6.8 (1, d), 7.10 (1,m), 7.9 (1,m), 8.18 (1,m), 8.53 (1, d); MS: m/e 399 (M++1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06380218B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-69f1ae3b35764eab97441cbfe06eb53a |
| Source note | uspto-grants-2002_04 |