2-[4-(Aminomethyl)phenyl]propan-2-ol → HCID 22612084, compound

HRID 844095Notes

Reaction equation

HRID 844095 reaction equation
[O:1]1[C:6]2[CH:7]=[CH:8][C:9]([O:11][C:12]3[N:20]=[CH:19][CH:18]=[CH:17][C:13]=3[C:14]([OH:16])=O)=[CH:10][C:5]=2[O:4][CH2:3][CH2:2]1.[NH2:21][CH2:22][C:23]1[CH:28]=[CH:27][C:26]([C:29]([OH:32])([CH3:31])[CH3:30])=[CH:25][CH:24]=1>>[O:1]1[C:6]2[CH:7]=[CH:8][C:9]([O:11][C:12]3[N:20]=[CH:19][CH:18]=[CH:17][C:13]=3[C:14]([NH:21][CH2:22][C:23]3[CH:28]=[CH:27][C:26]([C:29]([OH:32])([CH3:30])[CH3:31])=[CH:25][CH:24]=3)=[O:16])=[CH:10][C:5]=2[O:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 101542112-[4-(Aminomethyl)phenyl]propan-2-olHCID 22612347HCID 22612347, compound

Product 1

HCID 22612084HCID 22612084, compound

Procedure

Prepared from 2-(2,3-Dihydro-benzo[1,4]dioxin-6-yloxy)-nicotinic acid and 2-(4-Aminomethyl-phenyl)-propan-2-ol. MS: m/e 421 (M++1), 1HNMR (CDCl3) δ1.51 (6H, s), 4.24 (4H, s), 4.66(2H, d), 6.57 (1H, dd), 6.85 (1h, d), 7.11(1H, dd), 7.28(2H, d), 7.41(2H, d), 8.19(2H, m), 8.61(1H, d).

Sources & evidence

ORD record
ord-61c7a61f90964d28a9fc10926ded4456
Source dataset
uspto-grants-2002_04
Patent number
US06380218B1

Reaction notes

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