HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Nitrophenylboronic Acid → 5-(3-Nitro-phenyl)-1,3-dihydro-benzoimidazol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Nitrophenylboronic Acid | HCID 1677 | — |
| Reactant | 5-Bromo-1,3-dihydro-2H-benzimidazol-2-one | HCID 12228060 | — |
| Product | 5-(3-Nitro-phenyl)-1,3-dihydro-benzoimidazol-2-one | HCID 9795031 | — |
Reaction Steps
Prepared from 5-bromo-1,3-dihydro-benzoimidazol-2-one and 3-nitro-phenyl boronic acid in the same fashion as that of Example 5. White solid: mp 324-325° C.; 1H-NMR(DMSO-d6) δ10.8 (s, 2H), 8.4 (m, 1H), 8.15 (d, 1H, J=7.5 Hz), 8.1 (d, 1H, J=7.5 Hz), 7.7 (t, 1H, J=7.5 Hz), 7.35 (d, 1H, J=7.5 Hz), 7.3 (s, 1H), 7.05 (d, 1H, J=7.5 Hz); MS (ES) m/z 254 ([M−H]−, 100%); Anal. Calc. For C13H9N3O3: C, 61.18; H, 3.55; N, 16.46. Found: C, 60.5; H, 3.69; N, 15.53.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06380235B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-38d4e9ea31c64e398577aabf53540393 |
| Source note | uspto-grants-2002_04 |